Tryptamines

Tryptamines — EU Research Compounds

HPLC-verified tryptamine reference standards — 4-AcO-DMT, 4-HO-MET, 5-MeO-DMT, AMT, DPT and more. ≥99% purity, CoA included, EU dispatch.

≥99% HPLC Purity CoA Every Order EU Warehouse Same-Day Dispatch

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Tryptamines — 11 Compounds Available

POPULAR

4-AcO-DMT

4-AcO-DMT (O-Acetylpsilocin) — conceived by Albert Hofmann in 1963. Formula C14H18N2O2, Molar Mass 246.31 g·mol−1. Fumarate form, ≥99% purity.

From €39

4-PrO-DMT

4-PrO-DMT — cutting edge in tryptamine exploration (emerged 2019). Formula C15H20N2O2, Molar Mass 260.337 g·mol−1. Fumarate form.

From €38

4-HO-MET

4-HO-MET (4-Hydroxy-N-methyl-N-ethyltryptamine) — originating from Alexander Shulgin's labs. Formula C13H18N2O, Molar Mass 218.300 g·mol−1.

From €38

4-HO-MiPT

4-HO-MiPT — novel tryptamine researched by Alexander Shulgin. Formula C14H20N2O, Molar Mass 232.327 g·mol−1. Fumarate form.

From €42

5-MeO-DMT

5-MeO-DMT — first synthesized in 1936. Formula C13H18N2O, Molar Mass 218.300 g·mol−1. Freebase form.

From €45

DPT

DPT (Dipropyltryptamine) — fascinating tryptamine with roots dating to the 1950s. Formula C16H24N2, Molar Mass 244.382 g·mol−1. HCl Salt form.

From €108

AMT

AMT (Alpha-Methyltryptamine / α-MT) — tryptamine family compound structurally related to serotonin, DMT, and psilocybin.

From €40

AMT Powder

AMT (Alpha-Methyltryptamine) powder — synthetic indole alkaloid from the tryptamine class.

From €38

NEW

5-MeO-MiPT

5-MeO-MiPT freebase powder. 5-methoxy-substituted tryptamine reference compound.

From €33

NEW

5-MeO-MALT

5-MeO-MALT fumarate powder. 5-methoxy substituted tryptamine reference standard.

From €26

BUNDLE

Variety Pack — Tryptamines

Curated tryptamine bundle: 4-HO-MET, 5-MeO-MALT, and 4-AcO-DMT fumarate reference standards.

From €64

About Tryptamines

Tryptamines are a class of indole-ring compounds biosynthetically derived from the amino acid tryptophan. They include endogenous neurotransmitters (serotonin, DMT, melatonin) as well as many synthetic reference compounds widely used in neurochemistry, pharmacology, and forensic analytical research.

Tryptamines primarily interact with serotonin receptors, particularly 5-HT2A, 5-HT2B, and 5-HT2C subtypes, though many also bind to 5-HT1A, 5-HT3, and other monoamine receptors. The indole ring can be substituted at the 4- or 5-position with hydroxy, methoxy, or acetoxy groups, creating compounds with distinct receptor binding profiles. 4-AcO-DMT (O-Acetylpsilocin) is one of the most-studied tryptamine reference standards due to its relationship to psilocybin metabolism.

Key Compounds in This Category

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4-AcO-DMT

O-Acetylpsilocin — psilocin prodrug standard

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4-HO-MET

4-Hydroxy-N-methyl-N-ethyltryptamine

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5-MeO-DMT

5-Methoxy-N,N-dimethyltryptamine

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AMT

Alpha-methyltryptamine freebase

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DPT

Dipropyltryptamine hydrochloride

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Tryptamines — FAQ

What are tryptamines?

Tryptamines are indole-ring compounds derived from tryptophan. They include endogenous molecules like serotonin and melatonin, as well as synthetic research compounds like 4-AcO-DMT, 4-HO-MET, 5-MeO-DMT, and AMT. They primarily act at serotonin receptors (5-HT2A, 5-HT1A, 5-HT2C) and are widely used as reference standards in neurochemistry and forensic pharmacology.

What is the most popular tryptamine research compound?

4-AcO-DMT (O-Acetylpsilocin) is the most popular tryptamine research compound, closely followed by 4-HO-MET and 5-MeO-DMT. 4-AcO-DMT is particularly popular as it is the acetate ester of psilocin, making it a key substrate for psilocybin metabolism studies.

What tryptamines does Best Chems stock?

Best Chems stocks: 4-AcO-DMT fumarate, 4-HO-MET fumarate, 5-MeO-DMT fumarate, AMT freebase, DPT hydrochloride, 5-MeO-MiPT, 5-MeO-MALT, and a Tryptamine Variety Pack. All independently HPLC-tested to ≥99% purity with Certificate of Analysis.