Dissociatives

Dissociatives — EU Research Compounds

HPLC-verified dissociative research standards — 2-FDCK, O-PCE, calibrated keta spray formats. >99% purity, CoA included, EU warehouse.

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Dissociatives — 3 Compounds Available

2-FDCK Crystals
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2-FDCK Crystals

2-FDCK (deschloroketamine/fluoroketamine) — dissociative anesthetic analogue of ketamine. High-purity crystalline form.

From €45

2F-DCK Keta Spray

2F-DCK Keta Spray

2F-DCK in pre-calibrated nasal spray format delivering consistent dose per actuation.

From €55

O-PCE Powder
NEW

O-PCE Powder

O-PCE (Eticyclidone) for advanced research. Lab-tested for purity, fast discreet shipping.

From €50

About Dissociatives

Dissociatives are a class of compounds that act primarily as NMDA (N-methyl-D-aspartate) receptor antagonists by blocking the ion channel. The class includes arylcyclohexylamines such as ketamine and its analogs, as well as diarylethylamine compounds like MXE. They are used extensively as research tools in anesthesiology, neuroprotection, and NMDA receptor pharmacology.

The arylcyclohexylamine class (ketamine, 2-FDCK, DCK) and diarylethylamine class (O-PCE, DMXE) represent the two major structural families of NMDA-antagonist dissociatives. Their selectivity, potency, and duration of action vary significantly across the series, making them valuable substrates for NMDA receptor subtype selectivity studies, neuroprotection research, and anesthesiology pharmacology. Best Chems stocks both crystal powder forms and calibrated nasal spray formats for precise dosing research.

Key Compounds in This Category

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Dissociatives — FAQ

What are dissociatives?
Dissociatives are compounds that act primarily as NMDA receptor antagonists. The class includes arylcyclohexylamines (ketamine, 2-FDCK) and diarylethylamines (O-PCE). They are used as research tools in anesthesiology pharmacology, neuroprotection studies, and NMDA receptor characterization.
What is 2-FDCK and how does it differ from ketamine?
2-FDCK (2-Fluorodeschloroketamine) is an arylcyclohexylamine where the chlorine atom in ketamine is replaced by fluorine at the 2-position of the aromatic ring. This changes lipophilicity, receptor selectivity, and metabolic profile, making 2-FDCK a valuable substrate for comparative SAR studies with ketamine.
What dissociatives does Best Chems stock?
Best Chems stocks: 2-FDCK crystals (500mg–10g), 2F-DCK Keta Spray in calibrated nasal applicator format (10ml–100ml), and O-PCE powder. All independently HPLC-tested to >99% purity with Certificate of Analysis.